英(yīng)文(wén)名(míng)稱(chēng)：Reserpine
CAS號：50-55-5
分析標(biāo)準品,≥99.5%
分子(zǐ)式 C33H40N2O9 分子(zǐ)量(liáng)608.68

基本信息:

密(mì)度1.32
溶(róng)解(jiě)性 Soluble in DMSO (100 mM), chloroform (10 mg/ml), water (<1 mg/ml at 25° C), and ethanol (<1 mg/ml at 25° C).
存(cún)貯條件(jiàn) 儲(chǔ)存(cún)溫度2-8°C
描述
產(chǎn)品介(jiè)紹 Reserpine has displayed a capacity to inhibit the transport of biogenic amines into synaptic vesicles and adrenal chromaffin granules. The mechanism behind this inhibition has been illuminated as an irreversible binding to the vesicular amine transporter. Furthermore, Reserpine has been reported to interfere with dopamine transporter activity and potently inhibit synaptosomal dopamine uptake. Reserpine is an inhibitor of VMAT 2.
別名(míng) 蛇(shé)根(gēn)鹼(jiǎn);血(xiě)安平;蛇(shé)根(gēn)草素(sù);Serpalan; Serpasil; Hiserpia; Serpanray; Serpivite; Apoplon;3,4,5-Trimethoxybenzoyl methyl reserpate; (3β, 16β, 17α, 18β, 20α)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester
生化機理(lǐ) 抑製兒茶酚胺(catecholamines)和5-羥色胺(àn)（serotonin）的(dí)吸(xī)收(shōu)。
應用 An inhibitor of transport of biogenic amines into adrenal chromaffin granules