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英文名稱Anti-ALS2CR3/FITC
中(zhōng)文名稱(chēng):FITC標(biāo)記的肌萎縮側索硬化症(zhèng)相關蛋(dàn)白3抗(kàng)體
別 名(míng)ALS2CR3; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein;TRAK2_HUMAN; Trafficking kinesin-binding protein 2.
規格(gé):100ul
說(shuō) 明 書100ul
研究(jiū)領(lǐng)域細(xì)胞(bāo)生物 神經(jīng)生(shēng)物學 Alzheimer's
抗(kàng)體來(lái)源Rabbit
克(kè)隆類型Polyclonal
交(jiāo)叉(chā)反(fǎn)應 Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
產(chǎn)品應(yīng)用ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子(zǐ) 量(liáng)101kDa
性(xìng) 狀Lyophilized or Liquid
濃 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human ALS2CR3 (701-800aa)
亞 型IgG
純(chún)化方(fāng)法(fǎ)affinity purified by Protein A
儲 存(cún) 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保(bǎo)存條(tiáo)件(jiàn)Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹background:
ALS2CR3 may regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR
Function:
May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR
Subunit:
Interacts with GABA-A receptor and O-GlcNAc transferase. Interacts with HGS (By similarity). Interacts with RHOT1/Miro-1 and RHOT2/Miro-2.
Subcellular Location:
Cytoplasm (By similarity). Early endosome (By similarity). Mitochondrion (By similarity). Note=Colocalizes with MGARP at the mitochondria. Translocates from the cytoplasm to the mitochondria in a MGARP-dependent manner
Tissue Specificity:
Widely expressed, with highest expression in heart.
Post-translational modifications:
O-glycosylated
Similarity:
Contains 1 HAP1 N-terminal domain.
Database links:
UniProtKB/Swiss-Prot: O60296.2
中(zhōng)文名稱(chēng):FITC標(biāo)記的肌萎縮側索硬化症(zhèng)相關蛋(dàn)白3抗(kàng)體
別 名(míng)ALS2CR3; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein;TRAK2_HUMAN; Trafficking kinesin-binding protein 2.
詳(xiáng)細(xì)介紹：
規格(gé):100ul
說(shuō) 明 書100ul
研究(jiū)領(lǐng)域細(xì)胞(bāo)生物 神經(jīng)生(shēng)物學 Alzheimer's
抗(kàng)體來(lái)源Rabbit
克(kè)隆類型Polyclonal
交(jiāo)叉(chā)反(fǎn)應 Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
產(chǎn)品應(yīng)用ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子(zǐ) 量(liáng)101kDa
性(xìng) 狀Lyophilized or Liquid
濃 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human ALS2CR3 (701-800aa)
亞 型IgG
純(chún)化方(fāng)法(fǎ)affinity purified by Protein A
儲 存(cún) 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保(bǎo)存條(tiáo)件(jiàn)Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相關(guān)資(zī)料：
產品介紹background:
ALS2CR3 may regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR
Function:
May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR
Subunit:
Interacts with GABA-A receptor and O-GlcNAc transferase. Interacts with HGS (By similarity). Interacts with RHOT1/Miro-1 and RHOT2/Miro-2.
Subcellular Location:
Cytoplasm (By similarity). Early endosome (By similarity). Mitochondrion (By similarity). Note=Colocalizes with MGARP at the mitochondria. Translocates from the cytoplasm to the mitochondria in a MGARP-dependent manner
Tissue Specificity:
Widely expressed, with highest expression in heart.
Post-translational modifications:
O-glycosylated
Similarity:
Contains 1 HAP1 N-terminal domain.
Database links:
UniProtKB/Swiss-Prot: O60296.2
