首頁(yè) > 產品中心 > 科研抗體 > 標(biāo)記(jì)一抗(kàng)
產品(pǐn)中心
標(biāo)記一抗(kàng)
FITC標記(jì)的鐵(tiě)蛋白Fe65樣(yàng)蛋白(bái)2抗(kàng)體(tǐ)
英(yīng)文名稱(chēng)Anti-APBB3/FITC
中文名稱:FITC標(biāo)記(jì)的鐵(tiě)蛋(dàn)白(bái)Fe65樣蛋(dàn)白(bái)2抗體
別(bié) 名FE65L2; Amyloid beta A4 precursor protein binding family B member 3; Amyloid beta A4 precursor protein-binding family B member 3; amyloid beta precursor protein binding family B member 3; amyloid precursor interacting protein; Apbb3; APBB3_HUMAN; Fe65 like protein 2; FE65L2; Protein Fe65-like 2; SRA.
規格:100ul
說 明 書100ul
研究(jiū)領域細(xì)胞(bāo)生(shēng)物 神經生物學(xué) 信號轉導(dǎo) Alzheimer's
抗體(tǐ)來源Rabbit
克隆(lóng)類(lèi)型(xíng)Polyclonal
交(jiāo)叉(chā)反應 Human, Mouse, Rat, Dog, Cow, Sheep,
產(chǎn)品應(yīng)用ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分(fēn) 子 量52kDa
性 狀Lyophilized or Liquid
濃 度(dù)1mg/ml
免(miǎn) 疫 原(yuán)KLH conjugated synthetic peptide derived from human APBB3/FE65L2
亞 型IgG
純化方法(fǎ)affinity purified by Protein A
儲(chǔ) 存(cún) 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存(cún)條件(jiàn)Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹background:
Fe65L2 is a 486 amino acid protein that contains one WW domain and two PID domains. Binding to the intracellular domain of the ∫-Amyloid precursor protein, Fe65L2 is thought to modulate the internalization and, therefore, the accessibility and function of ∫-Amyloid. Via its ability to control the intracellular accumulation of ∫-Amyloid, Fe65L2 is thought to play a role in the pathogenesis of Alzheimer's disease. Fe65L2 exists as four alternatively spliced isoforms designated isoform I, isoform II, isoform III and isoform IV. Fe65L2 interacts with Amyloid-like protein and is encoded by a gene located on human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome
Function:
May modulate the internalization of beta-amyloid precursor protein.
Subunit:
Binds to the intracellular domain of the beta-amyloid precursor protein. Also binds to APP-like proteins.
Tissue Specificity:
Expressed in various tissues.
Similarity:
Contains 2 PID domains.
Contains 1 WW domain.
中文名稱:FITC標(biāo)記(jì)的鐵(tiě)蛋(dàn)白(bái)Fe65樣蛋(dàn)白(bái)2抗體
別(bié) 名FE65L2; Amyloid beta A4 precursor protein binding family B member 3; Amyloid beta A4 precursor protein-binding family B member 3; amyloid beta precursor protein binding family B member 3; amyloid precursor interacting protein; Apbb3; APBB3_HUMAN; Fe65 like protein 2; FE65L2; Protein Fe65-like 2; SRA.
詳(xiáng)細(xì)介紹：
規格:100ul
說 明 書100ul
研究(jiū)領域細(xì)胞(bāo)生(shēng)物 神經生物學(xué) 信號轉導(dǎo) Alzheimer's
抗體(tǐ)來源Rabbit
克隆(lóng)類(lèi)型(xíng)Polyclonal
交(jiāo)叉(chā)反應 Human, Mouse, Rat, Dog, Cow, Sheep,
產(chǎn)品應(yīng)用ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分(fēn) 子 量52kDa
性 狀Lyophilized or Liquid
濃 度(dù)1mg/ml
免(miǎn) 疫 原(yuán)KLH conjugated synthetic peptide derived from human APBB3/FE65L2
亞 型IgG
純化方法(fǎ)affinity purified by Protein A
儲(chǔ) 存(cún) 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存(cún)條件(jiàn)Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相關(guān)資料：
產(chǎn)品介紹background:
Fe65L2 is a 486 amino acid protein that contains one WW domain and two PID domains. Binding to the intracellular domain of the ∫-Amyloid precursor protein, Fe65L2 is thought to modulate the internalization and, therefore, the accessibility and function of ∫-Amyloid. Via its ability to control the intracellular accumulation of ∫-Amyloid, Fe65L2 is thought to play a role in the pathogenesis of Alzheimer's disease. Fe65L2 exists as four alternatively spliced isoforms designated isoform I, isoform II, isoform III and isoform IV. Fe65L2 interacts with Amyloid-like protein and is encoded by a gene located on human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome
Function:
May modulate the internalization of beta-amyloid precursor protein.
Subunit:
Binds to the intracellular domain of the beta-amyloid precursor protein. Also binds to APP-like proteins.
Tissue Specificity:
Expressed in various tissues.
Similarity:
Contains 2 PID domains.
Contains 1 WW domain.
- 上一(yī)條(tiáo)：FITC標記的(dí)鐵蛋白Fe65樣蛋(dàn)白(bái)1抗體(tǐ)
- 下(xià)一(yī)條：FITC標記(jì)的(dí)β澱粉樣蛋白前體(tǐ)蛋(dàn)白(bái)結合(hé)蛋(dàn)白(bái)2抗(kàng)體(tǐ)
