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標(biāo)記一(yī)抗
FITC標記的抑製蛋白(bái)結(jié)構(gòu)域(yù)蛋(dàn)白4抗(kàng)體
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2017-5-2 瀏(liú)覽次(cì)數：1570
英文名稱(chēng)Anti-ARRDC4/FITC
中文(wén)名稱:FITC標記(jì)的抑(yì)製(zhì)蛋白(bái)結(jié)構(gòu)域(yù)蛋(dàn)白4抗(kàng)體(tǐ)
別 名(míng)ARRDC 4; Arrestin domain containing protein 4; ARRD4_HUMAN.
規格:100ul
說 明 書(shū)100ul
研(yán)究領(lǐng)域(yù)細胞生物 免(miǎn)疫學
抗體來源Rabbit
克隆類型Polyclonal
交叉(chā)反應(yīng) Human, Mouse, Rat, Chicken, Pig, Cow, Sheep,
產(chǎn)品應用(yòng)IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分(fēn) 子(zǐ) 量45 kDa
性 狀Lyophilized or Liquid
濃 度(dù)1mg/ml
免 疫 原(yuán)KLH conjugated synthetic peptide derived from human ARRDC4
亞(yà) 型IgG
純化方法(fǎ)affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保(bǎo)存(cún)條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品(pǐn)介紹background:
ARRDC4 belongs to the arrestin family. The arrestins are a family of proteins that are important for regulating signal transduction within cells. Arrestins are part of a conserved two step mechanism for regulating the activity of G-protein coupled receptors (GPCRs). In response to a stimulus, GPCRs activate a heterotrimeric G protein. In order to turn off this response, or adapt to a constant stimulus, activated receptors need to be silenced. The first step is phosphorylation by a class of serine/threonine kinases called G protein coupled receptor kinases (GRKs). This phosphorylation specifically marks the activated receptor for arrestin binding. Once arrestin is bound to the receptor it is unable to signal further. Recent research continues to expand the known actions of arrestins, which can bind to other classes of receptors and can directly activate signaling pathways on their own. Different arrestins (visual arrestin (or Arrestin 1), beta-arrestin 1 (or Arrestin 2) and beta-arrestin 2 (or Arrestin 3) can reduce the activity of their target GPCRs in several different ways
Similarity:
Belongs to the arrestin family.
Database links:
UniProtKB/Swiss-Prot: Q8NCT1.3
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
中文(wén)名稱:FITC標記(jì)的抑(yì)製(zhì)蛋白(bái)結(jié)構(gòu)域(yù)蛋(dàn)白4抗(kàng)體(tǐ)
別 名(míng)ARRDC 4; Arrestin domain containing protein 4; ARRD4_HUMAN.
詳(xiáng)細(xì)介紹：
規格:100ul
說 明 書(shū)100ul
研(yán)究領(lǐng)域(yù)細胞生物 免(miǎn)疫學
抗體來源Rabbit
克隆類型Polyclonal
交叉(chā)反應(yīng) Human, Mouse, Rat, Chicken, Pig, Cow, Sheep,
產(chǎn)品應用(yòng)IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分(fēn) 子(zǐ) 量45 kDa
性 狀Lyophilized or Liquid
濃 度(dù)1mg/ml
免 疫 原(yuán)KLH conjugated synthetic peptide derived from human ARRDC4
亞(yà) 型IgG
純化方法(fǎ)affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保(bǎo)存(cún)條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相關資料(liào)：
產(chǎn)品(pǐn)介紹background:
ARRDC4 belongs to the arrestin family. The arrestins are a family of proteins that are important for regulating signal transduction within cells. Arrestins are part of a conserved two step mechanism for regulating the activity of G-protein coupled receptors (GPCRs). In response to a stimulus, GPCRs activate a heterotrimeric G protein. In order to turn off this response, or adapt to a constant stimulus, activated receptors need to be silenced. The first step is phosphorylation by a class of serine/threonine kinases called G protein coupled receptor kinases (GRKs). This phosphorylation specifically marks the activated receptor for arrestin binding. Once arrestin is bound to the receptor it is unable to signal further. Recent research continues to expand the known actions of arrestins, which can bind to other classes of receptors and can directly activate signaling pathways on their own. Different arrestins (visual arrestin (or Arrestin 1), beta-arrestin 1 (or Arrestin 2) and beta-arrestin 2 (or Arrestin 3) can reduce the activity of their target GPCRs in several different ways
Similarity:
Belongs to the arrestin family.
Database links:
UniProtKB/Swiss-Prot: Q8NCT1.3
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
- 上(shàng)一(yī)條(tiáo)：FITC標記(jì)的抑(yì)製蛋白(bái)結構域(yù)蛋白3抗(kàng)體
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