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英文(wén)名稱Anti-ASAH2/FITC
中文(wén)名稱:FITC標(biāo)記的(dí)酰(xiān)基(jī)鞘氨醇(chún)脫酰酶(méi)2抗體
別 名Acylsphingosine deacylase 2; ASAH2; ASAH2_HUMAN; BCDase; hCD; HNAC1; LCDase; MGC129777; mitochondrial ceramidase; N acylsphingosine amidohydrolase (non lysosomal ceramidase) 2; N acylsphingosine amidohydrolase 2; N CDase; N-acylsphingosine amidohydrolase 2; N-CDase; NCDase; Neutral ceramidase soluble form; Non lysosomal ceramidase; Non-lysosomal ceramidase.
規格:100ul
說 明(míng) 書100ul
研(yán)究領(lǐng)域免疫學 神經生物學 信號(hào)轉(zhuǎn)導
抗體來源(yuán)Rabbit
克隆類型(xíng)Polyclonal
交(jiāo)叉反應(yīng) Human, Mouse, Rat, Dog, Rabbit,
產品應(yīng)用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量(liáng)86kDa
細(xì)胞定(dìng)位細胞(bāo)膜
性 狀Lyophilized or Liquid
濃(nóng) 度(dù)1mg/ml
免 疫(yì) 原KLH conjugated synthetic peptide derived from human ASAH2
亞 型IgG
純(chún)化方(fāng)法(fǎ)affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條(tiáo)件(jiàn)Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品(pǐn)介(jiè)紹(shào)background:
Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5. Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine, a precursor of the antiapoptotic factor sphingosine 1-phosphate. Probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regulating the levels of bioactive sphingolipid metabolites in the intestinal tract.
中文(wén)名稱:FITC標(biāo)記的(dí)酰(xiān)基(jī)鞘氨醇(chún)脫酰酶(méi)2抗體
別 名Acylsphingosine deacylase 2; ASAH2; ASAH2_HUMAN; BCDase; hCD; HNAC1; LCDase; MGC129777; mitochondrial ceramidase; N acylsphingosine amidohydrolase (non lysosomal ceramidase) 2; N acylsphingosine amidohydrolase 2; N CDase; N-acylsphingosine amidohydrolase 2; N-CDase; NCDase; Neutral ceramidase soluble form; Non lysosomal ceramidase; Non-lysosomal ceramidase.
詳(xiáng)細(xì)介(jiè)紹：
規格:100ul
說 明(míng) 書100ul
研(yán)究領(lǐng)域免疫學 神經生物學 信號(hào)轉(zhuǎn)導
抗體來源(yuán)Rabbit
克隆類型(xíng)Polyclonal
交(jiāo)叉反應(yīng) Human, Mouse, Rat, Dog, Rabbit,
產品應(yīng)用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量(liáng)86kDa
細(xì)胞定(dìng)位細胞(bāo)膜
性 狀Lyophilized or Liquid
濃(nóng) 度(dù)1mg/ml
免 疫(yì) 原KLH conjugated synthetic peptide derived from human ASAH2
亞 型IgG
純(chún)化方(fāng)法(fǎ)affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條(tiáo)件(jiàn)Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相關(guān)資(zī)料：
產品(pǐn)介(jiè)紹(shào)background:
Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5. Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine, a precursor of the antiapoptotic factor sphingosine 1-phosphate. Probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regulating the levels of bioactive sphingolipid metabolites in the intestinal tract.
