產品(pǐn)中(zhōng)心(xīn)
標(biāo)記一抗
英文名(míng)稱(chēng)Anti-ADAM15/FITC
中文名(míng)稱:FITC標(biāo)記(jì)的(dí)去(qù)整(zhěng)合(hé)素(sù)樣金屬蛋白(bái)酶15抗體
別 名(míng)A disintegrin and metalloproteinase domain 15; ADA15_HUMAN; ADAM 15; ADAM metallopeptidase domain 15; Adam15; and cysteine-rich protein 15; Disintegrin and metalloproteinase domain-containing protein 15; disintegrin-like; EC 3.4.24.; MDC 15; MDC-15; MDC15; Metalloprotease RGD disintegrin protein; Metalloproteinase like disintegrin like and cysteine rich protein 15; Metalloproteinase-like; Metargidin.
規格(gé):100ul
說 明(míng) 書100ul
研(yán)究(jiū)領(lǐng)域(yù)腫(zhǒng)瘤(liú) 細胞(bāo)生物 免疫(yì)學(xué) 信號(hào)轉導 細胞粘附分子 細胞(bāo)骨架 細(xì)胞外(wài)基(jī)質 泛素(sù)
抗體來源(yuán)Rabbit
克隆類型Polyclonal
交叉反(fǎn)應 Human,
產品(pǐn)應(yīng)用(yòng)Flow-Cyt=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量(liáng)70kDa
細胞定位細胞膜(mó)
性 狀Lyophilized or Liquid
濃(nóng) 度1mg/ml
免(miǎn) 疫(yì) 原(yuán)KLH conjugated synthetic peptide derived from human ADAM15
亞 型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存(cún) 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存(cún)條(tiáo)件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹(shào)background:
ADAM15 is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
中文名(míng)稱:FITC標(biāo)記(jì)的(dí)去(qù)整(zhěng)合(hé)素(sù)樣金屬蛋白(bái)酶15抗體
別 名(míng)A disintegrin and metalloproteinase domain 15; ADA15_HUMAN; ADAM 15; ADAM metallopeptidase domain 15; Adam15; and cysteine-rich protein 15; Disintegrin and metalloproteinase domain-containing protein 15; disintegrin-like; EC 3.4.24.; MDC 15; MDC-15; MDC15; Metalloprotease RGD disintegrin protein; Metalloproteinase like disintegrin like and cysteine rich protein 15; Metalloproteinase-like; Metargidin.
詳(xiáng)細介紹：
規格(gé):100ul
說 明(míng) 書100ul
研(yán)究(jiū)領(lǐng)域(yù)腫(zhǒng)瘤(liú) 細胞(bāo)生物 免疫(yì)學(xué) 信號(hào)轉導 細胞粘附分子 細胞(bāo)骨架 細(xì)胞外(wài)基(jī)質 泛素(sù)
抗體來源(yuán)Rabbit
克隆類型Polyclonal
交叉反(fǎn)應 Human,
產品(pǐn)應(yīng)用(yòng)Flow-Cyt=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量(liáng)70kDa
細胞定位細胞膜(mó)
性 狀Lyophilized or Liquid
濃(nóng) 度1mg/ml
免(miǎn) 疫(yì) 原(yuán)KLH conjugated synthetic peptide derived from human ADAM15
亞 型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存(cún) 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存(cún)條(tiáo)件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相(xiāng)關資料(liào)：
產品介紹(shào)background:
ADAM15 is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
