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英文名稱Anti-phospho-AKT1(Thr34)/FITC
中文(wén)名稱(chēng):FITC標記(jì)的磷(lín)酸(suān)化(huà)蛋(dàn)白激酶(méi)B抗(kàng)體
別(bié) 名AKT1 (phospho T34); p-AKT1 (phospho T34); AKT 1; AKT; AKT1; AKT-1; AKT1_HUMAN; C AKT; cAKT; MGC9965; MGC99656; Oncogene AKT1; PKB; PKB alpha; PKB-ALPHA; PRKBA; Protein Kinase B Alpha; Protein kinase B; Proto-oncogene c-Akt; RAC Alpha; RAC alpha serine/threonine protein kinase; RAC; RAC PK Alpha; Rac protein kinase alpha; RAC Serine/Threonine Protein Kinase; RAC-alpha serine/threonine-protein kinase; RAC-PK-alpha; v akt murine thymoma viral oncogene homolog 1; vAKT Murine Thymoma Viral Oncogene Homolog 1; AKT1_HUMAN.
規格:100ul
說 明 書(shū)100ul
產(chǎn)品類型(xíng)磷酸(suān)化抗體
研(yán)究領(lǐng)域腫瘤 免疫學 信號轉導 細胞(bāo)凋亡(wáng) 轉(zhuǎn)錄調節(jié)因子 激(jī)酶(méi)和磷酸酶
抗(kàng)體(tǐ)來源Rabbit
克隆(lóng)類(lèi)型Polyclonal
交叉(chā)反應(yīng) Human, Mouse, Rat,
產品(pǐn)應(yīng)用Flow-Cyt=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分(fēn) 子 量56kDa
細胞定(dìng)位細胞膜
性 狀Lyophilized or Liquid
濃(nóng) 度(dù)1mg/ml
免 疫 原KLH conjugated Synthesised phosphopeptide derived from human AKT1 around the phosphorylation site of Thr34
亞(yà) 型IgG
純(chún)化(huà)方法(fǎ)affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保(bǎo)存(cún)條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹background:
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011]
中文(wén)名稱(chēng):FITC標記(jì)的磷(lín)酸(suān)化(huà)蛋(dàn)白激酶(méi)B抗(kàng)體
別(bié) 名AKT1 (phospho T34); p-AKT1 (phospho T34); AKT 1; AKT; AKT1; AKT-1; AKT1_HUMAN; C AKT; cAKT; MGC9965; MGC99656; Oncogene AKT1; PKB; PKB alpha; PKB-ALPHA; PRKBA; Protein Kinase B Alpha; Protein kinase B; Proto-oncogene c-Akt; RAC Alpha; RAC alpha serine/threonine protein kinase; RAC; RAC PK Alpha; Rac protein kinase alpha; RAC Serine/Threonine Protein Kinase; RAC-alpha serine/threonine-protein kinase; RAC-PK-alpha; v akt murine thymoma viral oncogene homolog 1; vAKT Murine Thymoma Viral Oncogene Homolog 1; AKT1_HUMAN.
詳細(xì)介(jiè)紹(shào)：
規格:100ul
說 明 書(shū)100ul
產(chǎn)品類型(xíng)磷酸(suān)化抗體
研(yán)究領(lǐng)域腫瘤 免疫學 信號轉導 細胞(bāo)凋亡(wáng) 轉(zhuǎn)錄調節(jié)因子 激(jī)酶(méi)和磷酸酶
抗(kàng)體(tǐ)來源Rabbit
克隆(lóng)類(lèi)型Polyclonal
交叉(chā)反應(yīng) Human, Mouse, Rat,
產品(pǐn)應(yīng)用Flow-Cyt=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分(fēn) 子 量56kDa
細胞定(dìng)位細胞膜
性 狀Lyophilized or Liquid
濃(nóng) 度(dù)1mg/ml
免 疫 原KLH conjugated Synthesised phosphopeptide derived from human AKT1 around the phosphorylation site of Thr34
亞(yà) 型IgG
純(chún)化(huà)方法(fǎ)affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保(bǎo)存(cún)條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相(xiāng)關(guān)資料：
產品介紹background:
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011]
