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FITC標(biāo)記(jì)的(dí)中性(xìng)膽固(gù)醇(chún)酯水解(jiě)酶1抗體(tǐ)
英文名(míng)稱Anti-AADACL1/FITC
中文(wén)名稱:FITC標記的中(zhōng)性(xìng)膽(dǎn)固醇酯水(shuǐ)解酶(méi)1抗體
別 名(míng)Arylacetamide deacetylase like 1; Arylacetamide deacetylase-like 1; Kiaa1363; NCEH; Nceh1; NCEH1_HUMAN; Neutral cholesterol ester hydrolase 1; Neutral cholesterol ester hydrolase.
規格(gé):100ul
說 明(míng) 書(shū)100ul
研究(jiū)領(lǐng)域(yù)腫瘤(liú) 免疫(yì)學(xué) 信(xìn)號轉導(dǎo) 腫瘤(liú)細胞生物標(biāo)誌(zhì)物(wù)
抗(kàng)體(tǐ)來(lái)源(yuán)Rabbit
克(kè)隆(lóng)類(lèi)型Polyclonal
交叉反(fǎn)應 Human, Mouse, Rat,
產(chǎn)品應用(yòng)IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分(fēn) 子 量46kDa
細胞定(dìng)位細胞(bāo)膜(mó)
性 狀(zhuàng)Lyophilized or Liquid
濃 度1mg/ml
免(miǎn) 疫(yì) 原KLH conjugated synthetic peptide derived from human AADACL1
亞 型IgG
純(chún)化方(fāng)法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存(cún)條件(jiàn)Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹background:
The assembly of very-low-density lipoproteins (VLDLs) in the secretory apparatus of the hepatocyte relies on the mobilization of triacylglycerol (TAG) from the cytosolic pool by lipolysis and re-esterification. However, some of the re-esterified TAG products are returned to the cytosolic pool in the liver, which protects vulnerable body tissues from excess lipotoxic non-esterified fatty acids in the plasma. Some of the lipases involved in this process include arylacetamide deacetylase (AADAC) and its related proteins AADACL1 and AADACL2. AADAC, a single pass type II membrane protein of the endoplasmic reticulum, is expressed in hepatocytes, intestinal mucosal cells, pancreas and adrenal gland. It plays an important role in the metabolic activation of arylamine substrates to ultimate carcinogens. AADACL1 hydrolyzes the metabolic intermediate 2-acetyl monoalkylglycerol, and its inactivation results in disruption of ether lipid metabolism in cancer cells and impaired cell migration and tumor growth.
中文(wén)名稱:FITC標記的中(zhōng)性(xìng)膽(dǎn)固醇酯水(shuǐ)解酶(méi)1抗體
別 名(míng)Arylacetamide deacetylase like 1; Arylacetamide deacetylase-like 1; Kiaa1363; NCEH; Nceh1; NCEH1_HUMAN; Neutral cholesterol ester hydrolase 1; Neutral cholesterol ester hydrolase.
詳細介(jiè)紹：
規格(gé):100ul
說 明(míng) 書(shū)100ul
研究(jiū)領(lǐng)域(yù)腫瘤(liú) 免疫(yì)學(xué) 信(xìn)號轉導(dǎo) 腫瘤(liú)細胞生物標(biāo)誌(zhì)物(wù)
抗(kàng)體(tǐ)來(lái)源(yuán)Rabbit
克(kè)隆(lóng)類(lèi)型Polyclonal
交叉反(fǎn)應 Human, Mouse, Rat,
產(chǎn)品應用(yòng)IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分(fēn) 子 量46kDa
細胞定(dìng)位細胞(bāo)膜(mó)
性 狀(zhuàng)Lyophilized or Liquid
濃 度1mg/ml
免(miǎn) 疫(yì) 原KLH conjugated synthetic peptide derived from human AADACL1
亞 型IgG
純(chún)化方(fāng)法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存(cún)條件(jiàn)Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相(xiāng)關資(zī)料：
產品介紹background:
The assembly of very-low-density lipoproteins (VLDLs) in the secretory apparatus of the hepatocyte relies on the mobilization of triacylglycerol (TAG) from the cytosolic pool by lipolysis and re-esterification. However, some of the re-esterified TAG products are returned to the cytosolic pool in the liver, which protects vulnerable body tissues from excess lipotoxic non-esterified fatty acids in the plasma. Some of the lipases involved in this process include arylacetamide deacetylase (AADAC) and its related proteins AADACL1 and AADACL2. AADAC, a single pass type II membrane protein of the endoplasmic reticulum, is expressed in hepatocytes, intestinal mucosal cells, pancreas and adrenal gland. It plays an important role in the metabolic activation of arylamine substrates to ultimate carcinogens. AADACL1 hydrolyzes the metabolic intermediate 2-acetyl monoalkylglycerol, and its inactivation results in disruption of ether lipid metabolism in cancer cells and impaired cell migration and tumor growth.
- 上(shàng)一(yī)條：FITC標記的(dí)肌動(dòng)蛋白結合(hé)蛋白Girdin抗體
- 下(xià)一(yī)條：FITC標記的磷酸(suān)化蛋白激酶B2抗體
