產品(pǐn)中(zhōng)心(xīn)
一抗
英文(wén)名(míng)稱(chēng) Anti-ALDH1A2
中文(wén)名稱 乙(yǐ)醛(quán)脫(tuō)氫(qīng)酶2型(xíng)抗(kàng)體
別 名 L1A2_HUMAN; Aldehyde dehydrogenase family 1 member A2; ALDH1A2 aldehyde dehydrogenase 1 family, member A2; ALDH1A2; Aldh1a7; AV116159; MGC26444; RALDH 2; RALDH(II); Raldh1; RalDH2; RALDH2 T; Retinal dehydrogenase 2; Retinaldehyde dehydrogenase 2; Retinaldehyde specific dehydrogenase type 2; Retinaldehyde-specific dehydrogenase type 2.
濃(nóng) 度(dù) 1mg/1ml
規 格(gé) 0.2ml/200μg
抗體來源(yuán) Rabbit
克隆(lóng)類型 polyclonal
交叉(chā)反應 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, Monkey
產品(pǐn)類(lèi)型 一抗
研(yán)究領(lǐng)域(yù) 細(xì)胞生(shēng)物(wù) 神(shén)經(jīng)生物學
蛋(dàn)白分子量(liáng) predicted molecular weight: 57kDa
性 狀 Lyophilized or Liquid
免 疫(yì) 原(yuán) KLH conjugated synthetic peptide derived from human ALDH1A2
亞(yà) 型 IgG
純(chún)化(huà)方(fāng)法(fǎ) affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品(pǐn)應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蠟(là)切片需(xū)做(zuò)抗(kàng)原(yuán)修(xiū)復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品(pǐn)介紹 Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during the detoxification of alcohol-derived acetaldehyde; metabolism of corticosteroids, biogenic amines and neurotransmitters; and lipid peroxidation. ALDH1A1, also designated retinal dehydrogenase 1 (RalDH1 or RALDH1), aldehyde dehydrogenase family 1 member A1, aldehyde dehydrogenase cytosolic, ALDHII, ALDH-E1 or ALDH E1, is a retinal dehydrogenase that participates in the biosynthesis of retinoic acid (RA). There are two major liver isoforms of ALDH1 that can localize to cytosolic or mitochondrial space. The ALDH1A2 (RALDH2, RALDH2-T) gene produces three different transcripts and also catalyzes the synthesis of RA from retinaldehyde. ALDH1A3 (ALDH6, RALDH3, ALDH1A6) is a 37 kb gene that consists of 13 exons and produces a major transcript of approximately 3.5 kb most abundant in salivary gland, stomach and kidney. ALDH3A1 (stomach type, ALDH3, ALDHIII) forms a cytoplasmic homodimer that preferentially oxidizes aromatic aldehyde substrates. ALDH genes upregulate as a part of the oxidative stress response, and appear to be abundant in certain tumors that have an accelerated metabolism toward chemotherapy agents.
Function : Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Does metabolize octanal and decanal but does not metabolize citral, benzaldehyde, acetaldehyde and propanal efficiently.
Subunit : Homotetramer (By similarity).
Subcellular Location : Cytoplasm.
Similarity : Belongs to the aldehyde dehydrogenase family.
Database links : UniProtKB/Swiss-Prot: O94788.3
中文(wén)名稱 乙(yǐ)醛(quán)脫(tuō)氫(qīng)酶2型(xíng)抗(kàng)體
別 名 L1A2_HUMAN; Aldehyde dehydrogenase family 1 member A2; ALDH1A2 aldehyde dehydrogenase 1 family, member A2; ALDH1A2; Aldh1a7; AV116159; MGC26444; RALDH 2; RALDH(II); Raldh1; RalDH2; RALDH2 T; Retinal dehydrogenase 2; Retinaldehyde dehydrogenase 2; Retinaldehyde specific dehydrogenase type 2; Retinaldehyde-specific dehydrogenase type 2.
詳細介(jiè)紹(shào)：
濃(nóng) 度(dù) 1mg/1ml
規 格(gé) 0.2ml/200μg
抗體來源(yuán) Rabbit
克隆(lóng)類型 polyclonal
交叉(chā)反應 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, Monkey
產品(pǐn)類(lèi)型 一抗
研(yán)究領(lǐng)域(yù) 細(xì)胞生(shēng)物(wù) 神(shén)經(jīng)生物學
蛋(dàn)白分子量(liáng) predicted molecular weight: 57kDa
性 狀 Lyophilized or Liquid
免 疫(yì) 原(yuán) KLH conjugated synthetic peptide derived from human ALDH1A2
亞(yà) 型 IgG
純(chún)化(huà)方(fāng)法(fǎ) affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品(pǐn)應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蠟(là)切片需(xū)做(zuò)抗(kàng)原(yuán)修(xiū)復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
相關資料(liào)：
產品(pǐn)介紹 Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during the detoxification of alcohol-derived acetaldehyde; metabolism of corticosteroids, biogenic amines and neurotransmitters; and lipid peroxidation. ALDH1A1, also designated retinal dehydrogenase 1 (RalDH1 or RALDH1), aldehyde dehydrogenase family 1 member A1, aldehyde dehydrogenase cytosolic, ALDHII, ALDH-E1 or ALDH E1, is a retinal dehydrogenase that participates in the biosynthesis of retinoic acid (RA). There are two major liver isoforms of ALDH1 that can localize to cytosolic or mitochondrial space. The ALDH1A2 (RALDH2, RALDH2-T) gene produces three different transcripts and also catalyzes the synthesis of RA from retinaldehyde. ALDH1A3 (ALDH6, RALDH3, ALDH1A6) is a 37 kb gene that consists of 13 exons and produces a major transcript of approximately 3.5 kb most abundant in salivary gland, stomach and kidney. ALDH3A1 (stomach type, ALDH3, ALDHIII) forms a cytoplasmic homodimer that preferentially oxidizes aromatic aldehyde substrates. ALDH genes upregulate as a part of the oxidative stress response, and appear to be abundant in certain tumors that have an accelerated metabolism toward chemotherapy agents.
Function : Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Does metabolize octanal and decanal but does not metabolize citral, benzaldehyde, acetaldehyde and propanal efficiently.
Subunit : Homotetramer (By similarity).
Subcellular Location : Cytoplasm.
Similarity : Belongs to the aldehyde dehydrogenase family.
Database links : UniProtKB/Swiss-Prot: O94788.3
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