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英文名稱 Anti-BMP8b
中(zhōng)文名(míng)稱(chēng)： 骨形態發(fā)生蛋白8b抗(kàng)體
別 名 BMP-8; BMP-8B; BMP8; Bmp8b; BMP8B_HUMAN; Bone morphogenetic protein 8; Bone morphogenetic protein 8B; OP-2; OP2; Osteogenic protein 2.
濃(nóng) 度 1mg/1ml
規 格(gé) 0.2ml/200μg
抗體(tǐ)來源 Rabbit
克隆(lóng)類型 polyclonal
交(jiāo)叉(chā)反(fǎn)應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep
產品類型 一抗
研究(jiū)領(lǐng)域(yù) 細(xì)胞生物(wù) 發育生物(wù)學 信號轉導 幹細(xì)胞 生長因(yīn)子和(hé)激(jī)素
蛋白(bái)分(fēn)子量 predicted molecular weight: 16kDa
性 狀 Lyophilized or Liquid
免(miǎn) 疫(yì) 原 KLH conjugated synthetic peptide derived from human BMP8b
亞 型(xíng) IgG
純化(huà)方(fāng)法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應用(yòng) WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蠟(là)切片需做(zuò)抗原(yuán)修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保(bǎo)存條件(jiàn) Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹 Bone morphogenic proteins (BMPs) are members of the TGF Beta superfamily. BMPs are involved in the induction of cartilage and bone formation. In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGF Beta receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 (also designated OP-2) is thought to be involved in early development, as detectable expression has not been found in adult organs.
Function : Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.
Subunit : Homodimer; disulfide-linked.
Subcellular Location : Secreted.
Similarity : Belongs to the TGF-beta family.
Database links : UniProtKB/Swiss-Prot: P34820.2
中(zhōng)文名(míng)稱(chēng)： 骨形態發(fā)生蛋白8b抗(kàng)體
別 名 BMP-8; BMP-8B; BMP8; Bmp8b; BMP8B_HUMAN; Bone morphogenetic protein 8; Bone morphogenetic protein 8B; OP-2; OP2; Osteogenic protein 2.
詳(xiáng)細(xì)介紹：
濃(nóng) 度 1mg/1ml
規 格(gé) 0.2ml/200μg
抗體(tǐ)來源 Rabbit
克隆(lóng)類型 polyclonal
交(jiāo)叉(chā)反(fǎn)應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep
產品類型 一抗
研究(jiū)領(lǐng)域(yù) 細(xì)胞生物(wù) 發育生物(wù)學 信號轉導 幹細(xì)胞 生長因(yīn)子和(hé)激(jī)素
蛋白(bái)分(fēn)子量 predicted molecular weight: 16kDa
性 狀 Lyophilized or Liquid
免(miǎn) 疫(yì) 原 KLH conjugated synthetic peptide derived from human BMP8b
亞 型(xíng) IgG
純化(huà)方(fāng)法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應用(yòng) WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蠟(là)切片需做(zuò)抗原(yuán)修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保(bǎo)存條件(jiàn) Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
相關(guān)資料：
產品介紹 Bone morphogenic proteins (BMPs) are members of the TGF Beta superfamily. BMPs are involved in the induction of cartilage and bone formation. In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGF Beta receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 (also designated OP-2) is thought to be involved in early development, as detectable expression has not been found in adult organs.
Function : Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.
Subunit : Homodimer; disulfide-linked.
Subcellular Location : Secreted.
Similarity : Belongs to the TGF-beta family.
Database links : UniProtKB/Swiss-Prot: P34820.2
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