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一(yī)抗
英(yīng)文(wén)名稱 Anti-BPY2
中(zhōng)文名稱： 睾(gāo)丸特異(yì)性鹼性蛋白Y2抗(kàng)體
別 名 Basic charge; Basic charge Y linked 2; Basic charge Y linked 2C; Basic protein on Y chromosome 2; BPY2A; BPY2B; BPY2C; Testis specific basic protein on Y 2; Testis specific basic protein Y 2; Testis-specific basic protein Y 2; Variable charge Y linked 2; Variably charged protein Y 2; VCY2; VCY2_HUMAN; VCY2A; VCY2B; VCY2C; Y-linked 2.
濃 度(dù) 1mg/1ml
規 格 0.2ml/200μg
抗體(tǐ)來源 Rabbit
克(kè)隆(lóng)類型 polyclonal
交叉反應 Human
產(chǎn)品類(lèi)型 一抗
研(yán)究(jiū)領(lǐng)域 細(xì)胞生物 發(fā)育生(shēng)物(wù)學 幹(gān)細胞(bāo)
蛋白分子(zǐ)量(liáng) predicted molecular weight: 12kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human BPY2
亞(yà) 型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石(shí)蠟切(qiē)片需做(zuò)抗原(yuán)修(xiū)復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存(cún)條件(jiàn) Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介(jiè)紹(shào) Mammalian spermatogenesis is a complex developmental process. Mutations at multiple loci and in structurally and functionally disparate genes in the genome affect gametogenesis. The analysis of mutations has provided insight into biochemical pathways required for completion of this process. The basic protein on Y chromosome 2 gene (BPY2, also designated VCY2) is located in a frequently deleted azoospermia factor c region. Three copies (paralogs) of the BPY2 gene (BPY2A, BPY2B, BPY2C) reside in the AZFc region. BPY2 protein expression is localized to the nuclei of spermatogonia, spermatocytes and round spermatids, but is absent from elongated spermatids. Impaired expression of BPY2 in infertile men suggests its involvement in male germ cell development. BPY2 interacts with MAP-1S, which shares homology with microtubule-associated proteins (MAPs), suggesting a role for BPY2 within the cytoskeletal network.
Subunit : Interacts with MAP1S. Interacts with UBE3A (via HECTdomain).
Tissue Specificity : Expressed exclusively in testis. Expressed in ejaculated spermatozoa of germ cell. Expressed in the nuclei of spermatogonia, spermatocytes, and round spermatids, except elongated spermatids (at protein level).
Similarity : Belongs to the VCX/VCY family.
Database links : UniProtKB/Swiss-Prot: O14599.2
中(zhōng)文名稱： 睾(gāo)丸特異(yì)性鹼性蛋白Y2抗(kàng)體
別 名 Basic charge; Basic charge Y linked 2; Basic charge Y linked 2C; Basic protein on Y chromosome 2; BPY2A; BPY2B; BPY2C; Testis specific basic protein on Y 2; Testis specific basic protein Y 2; Testis-specific basic protein Y 2; Variable charge Y linked 2; Variably charged protein Y 2; VCY2; VCY2_HUMAN; VCY2A; VCY2B; VCY2C; Y-linked 2.
詳細(xì)介紹：
濃 度(dù) 1mg/1ml
規 格 0.2ml/200μg
抗體(tǐ)來源 Rabbit
克(kè)隆(lóng)類型 polyclonal
交叉反應 Human
產(chǎn)品類(lèi)型 一抗
研(yán)究(jiū)領(lǐng)域 細(xì)胞生物 發(fā)育生(shēng)物(wù)學 幹(gān)細胞(bāo)
蛋白分子(zǐ)量(liáng) predicted molecular weight: 12kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human BPY2
亞(yà) 型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石(shí)蠟切(qiē)片需做(zuò)抗原(yuán)修(xiū)復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存(cún)條件(jiàn) Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
相(xiāng)關資(zī)料(liào)：
產品介(jiè)紹(shào) Mammalian spermatogenesis is a complex developmental process. Mutations at multiple loci and in structurally and functionally disparate genes in the genome affect gametogenesis. The analysis of mutations has provided insight into biochemical pathways required for completion of this process. The basic protein on Y chromosome 2 gene (BPY2, also designated VCY2) is located in a frequently deleted azoospermia factor c region. Three copies (paralogs) of the BPY2 gene (BPY2A, BPY2B, BPY2C) reside in the AZFc region. BPY2 protein expression is localized to the nuclei of spermatogonia, spermatocytes and round spermatids, but is absent from elongated spermatids. Impaired expression of BPY2 in infertile men suggests its involvement in male germ cell development. BPY2 interacts with MAP-1S, which shares homology with microtubule-associated proteins (MAPs), suggesting a role for BPY2 within the cytoskeletal network.
Subunit : Interacts with MAP1S. Interacts with UBE3A (via HECTdomain).
Tissue Specificity : Expressed exclusively in testis. Expressed in ejaculated spermatozoa of germ cell. Expressed in the nuclei of spermatogonia, spermatocytes, and round spermatids, except elongated spermatids (at protein level).
Similarity : Belongs to the VCX/VCY family.
Database links : UniProtKB/Swiss-Prot: O14599.2
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