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BCL2樣(yàng)10促(cù)凋(diāo)亡蛋(dàn)白(bái)抗體(tǐ)
英文(wén)名稱 Anti-BCL2L10
中文名稱(chēng)： BCL2樣10促凋亡(wáng)蛋白抗(kàng)體
別(bié) 名 Anti apoptotic protein NrH; Anti-apoptotic protein NrH; Apoptosis regulator Bcl B; Apoptosis regulator Bcl-B; B2L10_HUMAN; BCL B; Bcl-2-like protein 10; Bcl2 L 10; BCL2 like 10 (apoptosis facilitator); BCL2 like 10 protein; Bcl2-L-10; Bcl2l10; BCLB; Boo; Diva; MGC129810; MGC129811; Nrh.
濃 度 1mg/1ml
規 格 0.2ml/200μg
抗體(tǐ)來源(yuán) Rabbit
克隆(lóng)類(lèi)型 polyclonal
交叉反(fǎn)應(yīng) Human, Mouse, Rat, Chicken, Pig, Cow, Rabbit
產品類(lèi)型 一(yī)抗(kàng)
研究(jiū)領(lǐng)域(yù) 腫(zhǒng)瘤 細(xì)胞生(shēng)物 免疫學(xué) 細胞(bāo)凋亡 腫瘤細胞生(shēng)物(wù)標誌物(wù)
蛋白分(fēn)子(zǐ)量 predicted molecular weight: 22kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human BCL2L10
亞 型 IgG
純化方(fāng)法 affinity purified by Protein A
儲 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蠟切(qiē)片(piàn)需(xū)做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條(tiáo)件(jiàn) Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹 Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. BCL2L10 is a recently discovered anti-apoptotic member of the Bcl-2. Unlike the mouse homolog (also known as Diva/Boo) which is predominantly expressed in ovary and testis, the human BCL2L10 protein is widely expressed. Also, the human BCL2L10 functions by binding to and suppressing the apoptotic activity of Bax, whereas the mouse homolog binds Bak and also interacts with the apoptosis protein Apaf-1.
Function : Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK.
Subunit : Binds to Bcl-2, Bcl-X and BAX. Interacts with APAF1.
Subcellular Location : Mitochondrion. Nucleus membrane.
Tissue Specificity : Widely expressed in adult tissues.
Similarity : Belongs to the Bcl-2 family.
Database links : UniProtKB/Swiss-Prot: Q9HD36.2
中文名稱(chēng)： BCL2樣10促凋亡(wáng)蛋白抗(kàng)體
別(bié) 名 Anti apoptotic protein NrH; Anti-apoptotic protein NrH; Apoptosis regulator Bcl B; Apoptosis regulator Bcl-B; B2L10_HUMAN; BCL B; Bcl-2-like protein 10; Bcl2 L 10; BCL2 like 10 (apoptosis facilitator); BCL2 like 10 protein; Bcl2-L-10; Bcl2l10; BCLB; Boo; Diva; MGC129810; MGC129811; Nrh.
詳細(xì)介紹：
濃 度 1mg/1ml
規 格 0.2ml/200μg
抗體(tǐ)來源(yuán) Rabbit
克隆(lóng)類(lèi)型 polyclonal
交叉反(fǎn)應(yīng) Human, Mouse, Rat, Chicken, Pig, Cow, Rabbit
產品類(lèi)型 一(yī)抗(kàng)
研究(jiū)領(lǐng)域(yù) 腫(zhǒng)瘤 細(xì)胞生(shēng)物 免疫學(xué) 細胞(bāo)凋亡 腫瘤細胞生(shēng)物(wù)標誌物(wù)
蛋白分(fēn)子(zǐ)量 predicted molecular weight: 22kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human BCL2L10
亞 型 IgG
純化方(fāng)法 affinity purified by Protein A
儲 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蠟切(qiē)片(piàn)需(xū)做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條(tiáo)件(jiàn) Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
相(xiāng)關(guān)資料：
產品介紹 Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. BCL2L10 is a recently discovered anti-apoptotic member of the Bcl-2. Unlike the mouse homolog (also known as Diva/Boo) which is predominantly expressed in ovary and testis, the human BCL2L10 protein is widely expressed. Also, the human BCL2L10 functions by binding to and suppressing the apoptotic activity of Bax, whereas the mouse homolog binds Bak and also interacts with the apoptosis protein Apaf-1.
Function : Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK.
Subunit : Binds to Bcl-2, Bcl-X and BAX. Interacts with APAF1.
Subcellular Location : Mitochondrion. Nucleus membrane.
Tissue Specificity : Widely expressed in adult tissues.
Similarity : Belongs to the Bcl-2 family.
Database links : UniProtKB/Swiss-Prot: Q9HD36.2
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