產(chǎn)品中心(xīn)
一(yī)抗(kàng)
英文(wén)名稱(chēng) Anti-CD39/entpd1
中文(wén)名稱(chēng) CD39抗體
別 名 ATPDase; CD 39; CD39; CD39 antigen; DKFZp686D194; DKFZp686I093; Ecto apyrase; Ecto ATP diphosphohydrolase; Ecto-apyrase; Ecto-ATP diphosphohydrolase 1; Ecto-ATPase 1; Ecto-ATPDase 1; Ectonucleoside triphosphate
詳(xiáng)細介(jiè)紹：
濃 度 1mg/1ml
規 格 0.2ml/200μg
抗(kàng)體(tǐ)來源 Rabbit
克(kè)隆類(lèi)型(xíng) polyclonal
交叉反(fǎn)應(yīng) Human, Mouse, Rat, Pig, Cow, Sheep
產品(pǐn)類型 一抗
研(yán)究(jiū)領(lǐng)域 細(xì)胞(bāo)生(shēng)物 免疫(yì)學(xué) 蛋(dàn)白(bái)分(fēn)子量 predicted molecular weight: 58kDa
性(xìng) 狀(zhuàng) Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human CD39/entpd1
亞 型 IgG
純(chún)化(huà)方法(fǎ) affinity purified by Protein A
儲(chǔ) 存(cún) 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500
（石(shí)蠟切片需做(zuò)抗原(yuán)修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條(tiáo)件(jiàn) Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
相關資(zī)料：
產品介紹(shào) Members of the ecto-nucleoside triphosphate diphosphohydrolase (eNTPDase) protein family are glycosylated enzymes that hydrolyze nucleoside 5’-triphosphates and 5’-diphosphates in extracellcular space. The enzymatic activities of eNTPDase are dependent on cations such as magnesium and calcium. Members of this protein family differ in their affinities for triphosphates versus diphosphates as substrate material. CD39L3, also known as Ectonucleoside triphosphate diphosphohydrolase 3 or NTPDase 3, is a 529 amino acid multi-pass membrane protein that has a three-fold preference for hydrolysis of ATP over ADP. Both calcium and magnesium serve as cofactors for CD39L3’s extremely active extracellular nucleotide hydrolysis site. CD39L3 is expressed in spleen, prostate, brain and pancreas, though moderate to low expression is observed in most tissues, with the exception of liver and peripheral blood leukocytes.
Function : In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well.
Subunit : Homodimer; disulfide-linked (By similarity).
Subcellular Location : Membrane; Multi-pass membrane protein (Potential).
Tissue Specificity : Expressed primarily on activated lymphoid cells. Also expressed in endothelial tissues. Isoform 1 and isoform 3 are present in both placenta and umbilical vein, whereas isoform 2 is present in placenta only.
Post-translational modifications : The N-terminus is blocked.
Palmitoylated in the N-terminal part.
Similarity : Belongs to the GDA1/CD39 NTPase family.
Database links : UniProtKB/Swiss-Prot: P49961.1
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