產品中(zhōng)心
一(yī)抗(kàng)
肉毒(dú)鹼(jiǎn)O-乙(yǐ)酰基(jī)轉移酶
英文名稱(chēng) Anti-CRAT/CAT1
中文名(míng)稱(chēng) 肉(ròu)毒鹼O-乙酰(xiān)基(jī)轉移酶
別 名 CACP_HUMAN; Carnitine acetylase; Carnitine acetyltransferase; Carnitine O acetyltransferase; Carnitine O-acetyltransferase; CAT; CAT1; CrAT;
詳細介(jiè)紹：
濃(nóng) 度(dù) 1mg/1ml
規 格 0.2ml/200μg
抗(kàng)體來源 Rabbit
克隆類型(xíng) polyclonal
交(jiāo)叉反(fǎn)應(yīng) Human, Mouse, Rat, Chicken
產(chǎn)品(pǐn)類型 一抗(kàng)
研(yán)究(jiū)領域 心血管 細胞生物 免疫學 信(xìn)號轉導(dǎo) 脂蛋(dàn)白(bái) 新陳代(dài)謝
蛋(dàn)白(bái)分(fēn)子量 predicted molecular weight: 71kDa
性 狀(zhuàng) Lyophilized or Liquid
免(miǎn) 疫(yì) 原 KLH conjugated synthetic peptide derived from human CRAT/CAT1
亞 型 IgG
純(chún)化方(fāng)法 affinity purified by Protein A
儲(chǔ) 存(cún) 液(yè) Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產品應用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蠟(là)切片需(xū)做(zuò)抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存(cún)條(tiáo)件(jiàn) Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
相(xiāng)關資料(liào)：
產品介紹(shào) CRAT is a key enzyme in the metabolic pathway in mitochondria, peroxisomes and endoplasmic reticulum. CRAT catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acylCoA/CoA in the subcellular compartments. Two transcript variants encoding different isoforms have been found for this gene.
Function : Carnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria.
Subunit : Monomer.
Subcellular Location : Endoplasmic reticulum (Potential). Peroxisome (Potential). Mitochondrion inner membrane; Peripheral membrane protein; Matrix side (Potential).
Isoform 1: Mitochondrion (Potential).
Isoform 2: Peroxisome (Potential).
Tissue Specificity : Mostly in skeletal muscle, less in heart, liver and pancreas, only weakly detectable in brain, placenta, lung and kidney.
Similarity : Belongs to the carnitine/choline acetyltransferase family.
Database links : UniProtKB/Swiss-Prot: P43155.5
