產(chǎn)品中(zhōng)心(xīn)
一(yī)抗
英文名稱 Anti-C20orf20
中(zhōng)文名稱 20號(hào)染(rǎn)色(sè)體(tǐ)開(kāi)放閱(yuè)讀(dú)框(kuàng)20抗體(tǐ)
別 名 C20orf20; Chromosome 20 open reading frame 20; Eaf7; FLJ10914; MRG (MORF4 related gene) binding protein; MRG binding protein; MRG-binding protein; MRG/MORF4L binding protein; MRG15BP; MRGBP; MRGBP_HUMAN;
詳(xiáng)細(xì)介(jiè)紹：
濃 度 1mg/1ml
規 格 0.2ml/200μg
抗體來(lái)源 Rabbit
克(kè)隆(lóng)類(lèi)型(xíng) polyclonal
交叉(chā)反應 Human, Mouse, Rat
產(chǎn)品(pǐn)類(lèi)型 一抗(kàng)
研究領(lǐng)域 細胞(bāo)生物(wù) 免疫學
蛋白分(fēn)子量 predicted molecular weight: 22kDa
性 狀 Lyophilized or Liquid
免 疫 原(yuán) KLH conjugated synthetic peptide derived from human C20orf20
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石(shí)蠟切(qiē)片(piàn)需做抗原(yuán)修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保(bǎo)存(cún)條(tiáo)件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
相(xiāng)關資料：
產(chǎn)品介紹
Function : Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.
Subunit : Component of the NuA4 histone acetyltransferase complex which contains the catalytic subunit KAT5/TIP60 and the subunits EP400, TRRAP/PAF400, BRD8/SMAP, EPC1, DMAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, ING3, actin, ACTL6A/BAF53A, MORF4L1/MRG15, MORF4L2/MRGX, MRGBP, YEATS4/GAS41, VPS72/YL1 and MEAF6. The NuA4 complex interacts with MYC and the adenovirus E1A protein. MRGBP may interact directly with MORF4L1/MRG15 and MORF4L2/MRGX.
Subcellular Location : Nucleus.
Similarity : Belongs to the EAF7 family.
Database links : UniProtKB/Swiss-Prot: Q9NV56.1
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