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一抗
英(yīng)文名稱(chēng) Anti-CPA3/MC-CPA
中(zhōng)文(wén)名稱 肥(féi)大細胞羧肽酶(méi)A3抗體
別 名 carboxypeptidase A; Carboxypeptidase A3; carboxypeptidase A3 mast cell; CBPA3_HUMAN; Cpa3; Mast cell carboxypeptidase A; mast cell carboxypeptidase A3; MC CPA; MC-CPA.
詳細(xì)介(jiè)紹(shào)：
濃(nóng) 度 1mg/1ml
規(guī) 格 0.2ml/200μg
抗體來(lái)源(yuán) Rabbit
克(kè)隆類型 polyclonal
交叉反應(yīng) Human, Mouse, Rat
產品類型 一抗
研究(jiū)領(lǐng)域 細胞(bāo)生(shēng)物 發育生物(wù)學 信號(hào)轉導 幹細胞(bāo)
蛋(dàn)白分(fēn)子量 predicted molecular weight: 36kDa
性(xìng) 狀 Lyophilized or Liquid
免 疫(yì) 原(yuán) KLH conjugated synthetic peptide derived from Human CPA3/MC-CPA
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存(cún) 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石(shí)蠟(là)切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保(bǎo)存條(tiáo)件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
相關資(zī)料(liào)：
產(chǎn)品(pǐn)介(jiè)紹(shào) Carboxypeptidase A (CPA) is a pancreatic exopeptidase which hydrolyses the peptide bond adjacent to the C-terminal end in polypeptide chains. Mast cell carboxypeptidase A (MC-CPA), a part of the peptidase M14 family, is a highly conserved metalloprotease localized to the secretory granules, along with trytases and chymases. MC-CPA is stored as an active enzyme in the granule and is released, along with other inflammatory mediators, upon mast cell degranulation. MC-CPA mirrors pancreatic carboxypeptidase A in cleaving COOH-terminal aromatic and aliphatic amino acid residues. The optimum pH of MC-CPA is between neutral and basic, depending upon the substrate. The MC-CPA gene, CPA3, resides on chromosome 3 and contains 11 exons.
Subcellular Location : Cytoplasmic vesicle > secretory vesicle. Secretory granules.
Similarity : Belongs to the peptidase M14 family.
Database links : UniProtKB/Swiss-Prot: P15088.2
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