產品(pǐn)中心(xīn)
一抗(kàng)
尾(wěi)型同源(yuán)盒(hé)轉(zhuǎn)錄(lù)因子(zǐ)4抗體
英文名(míng)稱 Anti-CDX4
中文(wén)名稱 尾型(xíng)同源盒轉(zhuǎn)錄(lù)因(yīn)子4抗體(tǐ)
別(bié) 名 Caudal-type homeobox protein 4; CDX4; CDX4_HUMAN; Homeobox protein CDX-4.
詳(xiáng)細介紹：
濃(nóng) 度 1mg/1ml
規 格 0.2ml/200μg
抗(kàng)體(tǐ)來源(yuán) Rabbit
克(kè)隆類(lèi)型(xíng) polyclonal
交叉反應(yīng) Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep
產(chǎn)品(pǐn)類(lèi)型 一(yī)抗
研(yán)究(jiū)領域 細(xì)胞生物(wù) 幹細胞 表(biǎo)觀(guān)遺(yí)傳學
蛋(dàn)白(bái)分子(zǐ)量 predicted molecular weight: 30kDa
性(xìng) 狀(zhuàng) Lyophilized or Liquid
免(miǎn) 疫 原(yuán) KLH conjugated synthetic peptide derived from Human CDX4
亞 型 IgG
純(chún)化方法 affinity purified by Protein A
儲(chǔ) 存(cún) 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石(shí)蠟切(qiē)片需(xū)做抗原(yuán)修(xiū)復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保(bǎo)存條件(jiàn) Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
相關資料(liào)：
產品介(jiè)紹(shào) Cdx1, Cdx2 and Cdx4 are members of the caudal-type homeobox family of genes, which are homologs of the Drosophila “caudal” gene required for anterior-posterior regional identity. The proteins encoded by these genes are transcription factors which play an important role in development by regulating the expression of Hox genes. Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. Cdx4 is a major positive regulator of the expression of all Hox family members. Due to its critical role as a regulator, Cdx4 is a direct target of the canonical Wnt pathway. The loss of Cdx4 can result in the development of an expanded hindbrain, while the overexpression of Cdx4 may cause the hindbrain to lose its distinct segmental features and resemble the spinal cord.
Subcellular Location : Nucleus.
Similarity : Belongs to the Caudal homeobox family.
Contains 1 homeobox DNA-binding domain.
Database links : UniProtKB/Swiss-Prot: O14627.1
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