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磷酸(suān)化鈣調(tiáo)磷(lín)酸(suān)酶B亞(yà)基B1抗體
英(yīng)文名稱(chēng) Anti-Phospho-Calcineurin B (Tyr106)
中(zhōng)文名稱 磷酸化(huà)鈣(gài)調(tiáo)磷(lín)酸酶B亞基B1抗體(tǐ)
別(bié) 名 Calcineurin B (phospho Y106); Calcineurin B (phospho Tyr106); p-Calcineurin B (Tyr106); Calcineurin subunit B type 1; CALNB1; CANB1_HUMAN; Cna2; CNB; CNB1; OTTHUMP; OTTHUMP; Ppp3r1; PPP3R1 protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform; alpha isoform (calcineurin B, type I); calcineurin B, type I (19kDa); protein phosphatase3 (formerly2B), regulatory subunit B, alpha isoform antibody Protein phosphatase 2B regulatory subunit 1; Protein phosphatase 2B regulatory subunit B alpha; protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform (calcineurin B, type I); Protein phosphatase 3 regulatory subunit B alpha; Protein phosphatase 3 regulatory subunit B alpha isoform 1.
詳細介(jiè)紹(shào)：
濃(nóng) 度(dù) 1mg/1ml
規 格(gé) 0.1ml/100μg
抗(kàng)體(tǐ)來源 Rabbit
克隆(lóng)類(lèi)型(xíng) polyclonal
交叉反(fǎn)應 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, Fruit Fly, Danio rerio
產品(pǐn)類型 一抗 磷酸(suān)化(huà)抗(kàng)體
研(yán)究領域
蛋(dàn)白(bái)分(fēn)子量(liáng) predicted molecular weight: 19kDa
性 狀 Lyophilized or Liquid
免(miǎn) 疫 原(yuán) KLH conjugated synthesised phosphopeptide derived from human Calcineurin B around the phosphorylation site of Tyr106
亞 型 IgG
純化(huà)方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產品(pǐn)應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蠟切(qiē)片(piàn)需做抗(kàng)原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條(tiáo)件(jiàn) Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
相(xiāng)關資(zī)料：
產品介(jiè)紹 In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunit have been identified, designated PP1, PP2A, PP2B and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4), is a putative member of a novel PP family. The PP2B family comprises subfamily members PP2B-A alpha, PP2B-A Beta and PP2B-A Gamma. Two additional regulatory subunits been identified, designated PP2B-B1 and PP2B-B2.
Function : Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.
Subunit : Composed of a catalytic subunit (A) and a regulatory subunit (B).
Similarity : Belongs to the calcineurin regulatory subunit family. Contains 4 EF-hand domains.
Database links : UniProtKB/Swiss-Prot: P63098.2
