產品中(zhōng)心(xīn)
酶(méi)類
| 編號 |
產品(pǐn)名(míng)稱(chēng) |
英文(wén)名(míng)稱(chēng) |
規(guī)格(gé) |
CAS號 |
包(bāo)裝(zhuāng) |
|
YS-1246 |
丁酰膽鹼(jiǎn)酯(zhǐ)酶(méi) |
BCHE |
BR,4u/mg |
9001-08-5 |
500U |
簡介:
丁(dīng)酰膽鹼酯酶/BCHE/BUCHEBR,4u/mg500u,Sigma-Aldrich,Amresco,Amersham,Serva,AppliChem等品牌(pái),9001/8/52~8℃
詳細介紹:
中文(wén)名稱: 丁(dīng)酰膽(dǎn)鹼酯酶(méi)
英文名(míng)稱: BCHE
其他(tā)英文(wén)名稱(chēng): BuCHE ;Cholinesterase,butyryl(Horse serum) ;Acylcholine acyl-hydrolase;Choline esterase, butyryl;Pseudocholinesterase
產品規格(gé): BR,4u/mg
包裝: 500U
CAS號:9001-08-5
分子(zǐ)量(liáng):~440000
級別:BR
相關(guān)資料(liào):
產(chǎn)品描述(shù):It catalyzes the hydrolysis of a number of choline esters according to the following reaction:Acylcholine+H2O to choline+acid.It is a tetrameric glycoprotein with four subunits of equal size,each having a molecular weight of 110KDa.Butyryl cholinesterase hydrolyzes butyrylcholine four times more rapidly than acetylcholine.It is inhibited by 10-5 M physostigmine,numerous organophosphate esters,the carbamate derivates and quaternary ammonium saltsunit hydrolyzes 1umole of acetylchoine per minute at 25℃, pH7.4
性(xìng)狀:淡褐(hè)色(sè)粉(fěn)末(mò)。膽鹼酯酶有2種(zhǒng):AChE和(hé)丁(dīng)酰膽鹼(jiǎn)酯(zhǐ)酶(BuChE)。兩者(zhě)的(dí)基(jī)因結構,氨(ān)基酸(suān)序列及(jí)空(kōng)間三維結(jié)構均(jūn)顯示了(liǎo)很(hěn)高的(dí)同(tóng)源性(xìng)。二(èr)者的(dí)主(zhǔ)要(yào)差異(yì)在於,AChE水解(jiě)乙(yǐ)酰膽鹼(ACh)和(hé)乙酰(xiān)硫(liú)代(dài)膽鹼(jiǎn)(ATCh)比丙酰膽鹼(jiǎn)(PrCh)快,對丁酰膽鹼(BuCh)和丁酰硫代膽(dǎn)鹼(BuTCh)沒(méi)有(yǒu)明顯的(dí)水(shuǐ)解(jiě)作用(yòng)。丁(dīng)酰膽鹼(jiǎn)酯(zhǐ)酶(méi)與(yǔ)乙(yǐ)酰膽鹼(jiǎn)酯酶的(dí)顯色反應原理(lǐ)是完(wán)全(quán)一(yī)樣的。丁(dīng)酰膽(dǎn)鹼(jiǎn)酯酶具有靈(líng)敏度(dù)更高(gāo)的優(yōu)點
用(yòng)途:生化研(yán)究。是一(yī)類(lèi)糖蛋(dàn)白(bái),水解(jiě)乙(yǐ)酸(suān)膽(dǎn)鹼。是(shì)生物神經傳導中的(dí)一種(zhǒng)關(guān)鍵性(xìng)酶(méi),同時又(yòu)是有機(jī)磷和氨(ān)基(jī)甲(jiǎ)酸(suān)酯殺蟲劑的(dí)靶(bǎ)標。可以使包含有神經(jīng)毒劑(jì),殺蟲劑和化(huà)學熔(róng)劑(jì)的(dí)有機磷酸(suān)酯(zhǐ)中(zhōng)性化(huà),從而不(bù)受神經(jīng)毒劑(jì)的侵擾
保(bǎo)存(cún):2~8℃
- 上(shàng)一條:乙(yǐ)酰(xiān)膽(dǎn)鹼(jiǎn)酯(zhǐ)酶
- 下(xià)一條(tiáo):羧(suō)肽酶(méi)Y(酵(jiào)母)
