產品編(biān)號：Y0195

英(yīng)文(wén)名稱：Thiabendazole solution

CAS號 148-79-8 

100μg/ml,u=2%

分子(zǐ)式(shì) C10H7N3S 分(fēn)子量(liáng)201.25

基(jī)本信(xìn)息(xī):

密度  1.0000

熔點  304-305°C

溶解性(xìng)  Soluble in ethanol (1 mg/ml), DMF (50 mg/ml), chlorinated hydrocarbons (slightly), DMSO (40 mg/ml), and water (<1 mg/ml).

存貯條件  儲(chǔ)存溫度2-8℃

描(miáo)述

產品(pǐn)介紹  不(bù)溶於(yú)水，微溶於醇，丙酮(tóng)，易(yì)溶於(yú)乙(yǐ)醚(mí)，氯仿。在25℃，PH2.0的水中(zhōng)溶度(dù)為1%，在PH5-12水中溶(róng)解(jiě)度低於50ppm。丙(bǐng)酮中溶解度為(wéi)28G/L，苯2.3g/l，氯仿(fǎng)0.8g/L。甲(jiǎ)醇9.3g/L，二(èr)甲(jiǎ)基亞(yà)碸80g/L，二甲(jiǎ)基(jī)甲酰胺39.0g/L。在(zài)水，酸，鹼性(xìng)溶液中均穩(wěn)定(dìng)。無臭，無(wú)味(wèi)。

別(bié)名  噻苯咪(mī)唑(zuò);噻苯(běn)唑;2-(1,3-噻(sāi)唑-4-基)苯(běn)並(bìng)咪(mī)唑(zuò);2-(4-噻唑(zuò)基(jī))苯並(bìng)咪(mī)唑;2-(4-Thiazolyl)benzimidazole; 2-(thiazol-4-yl)benzimidazole; 2-(1,3-Thiazol-4-yl)benzimidazole; Mintezol; Mintesol; Omnizole;Lombristop; Thiabendazol

生(shēng)化機(jī)理  Thiabendazole inhibits anaerobic respiration at the level of mitochondrial helminth-specific enzyme. It acts as a quinol-fumarate reductase (QFR) inhibitor in ,C. jejuni and H. pylori, blocking quinol oxidation to quinone. Thiabendazole suppresses egg and larval production and may inhibit the subsequent development of eggs and larvae which are passed in feces2. A proposed route of biotransformation of thiabendazole is the CYP1A2-catalyzed hydroxylation to 5-hydroxythiabendazole, which is metabolized to glucuronide and sulfate conjugates.

應用  內(nèi)吸性(xìng)殺(shā)菌(jūn)劑(jì)。能(néng)防(fáng)止多(duō)種植(zhí)物(wù)的(dí)真菌(jūn)病害，用於處(chǔ)理(lǐ)收獲後的(dí)水果和蔬菜，可(kě)防止(zhǐ)貯存(cún)中發生的上些(xiē)病害(hài)，目前國(guó)內外已廣泛(fàn)應(yīng)用。例如(rú)，柑桔用500-1000ppm藥液浸(jìn)，防治(zhì)貯(zhù)存(cún)期青黴病(bìng)，綠(lǜ)黴病(bìng)。香(xiāng)蕉用(yòng)750-1500ppm藥(yào)液浸，防(fáng)治貯存期(qī)冠腐病(bìng)，炭疽(jū)病(bìng)，還可用(yòng)500-1000ppm藥液(yè)浸蘋果。梨(lí)，菠蘿，葡(pú)萄，草莓，甘藍，白(bái)菜，番茄，蘑(mó)菇，甜(tián)菜，甘蔗等，防治貯存期(qī)丙害。