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英(yīng)文名稱(chēng)Anti-KAL1/FITC
中(zhōng)文(wén)名稱(chēng):FITC標記(jì)的(dí)卡(qiǎ)爾曼綜合(hé)症基因(yīn)1抗(kàng)體(tǐ)
別 名(míng)KAL; Adhesion molecule-like X-linked; ADMLX; Anosmin-1; HHA; KAL1; KALIG 1; KALIG1; Kallmann syndrome 1 sequence (anosmin 1); Kallmann syndrome interval gene 1; Kallmann syndrome protein; KALM; KALM_HUMAN; KMS.
規格:100ul
說(shuō) 明(míng) 書100ul
研(yán)究領域神(shén)經生物(wù)學 信號轉導(dǎo) 細(xì)胞骨(gǔ)架 細胞外(wài)基質(zhì)
抗(kàng)體來源(yuán)Rabbit
克隆(lóng)類型(xíng)Polyclonal
交叉反(fǎn)應 Human, Rat, Chicken, Dog, Pig, Horse, Sheep,
產品應(yīng)用ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量74kDa
細(xì)胞(bāo)定位(wèi)細胞(bāo)膜(mó)
性(xìng) 狀Lyophilized or Liquid
濃(nóng) 度1mg/ml
免 疫 原(yuán)KLH conjugated synthetic peptide derived from human AF-6/l Afadin
亞 型IgG
純化(huà)方法affinity purified by Protein A
儲 存(cún) 液(yè)0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存(cún)條(tiáo)件(jiàn)Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈(fèi). When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
產品(pǐn)介(jiè)紹background:
May be an adhesion-like molecule with anti-protease activity
Function:
Has a dual branch-promoting and guidance activity, which may play an important role in the patterning of mitral and tufted cell collaterals to the olfactory cortex (By similarity). Chemoattractant for fetal olfactory epithelial cells.
Subunit:
Interacts with FGFR1; this interaction does not interfere with FGF2-binding to FGFR1. Binds heparin. Heparin may promote or interfere with KAL1-FGFR1-FGF2 complex formation depending on the sequential order of its binding to the various constituents. For instance, heparin-KAL1 interaction favors subsequent binding to pre-existing binary FGFR1-FGF2 complex, while heparin-FGF2 complex does not interact with KAL1-FGFR1.
Subcellular Location:
Cell membrane; Peripheral membrane protein. Secreted. Note=Proteolytic cleavage may release it from the cell surface into the extracellular space.
Tissue Specificity:
Expressed in the cerebellum (at protein level).
Post-translational modifications:
N-glycosylated.
中(zhōng)文(wén)名稱(chēng):FITC標記(jì)的(dí)卡(qiǎ)爾曼綜合(hé)症基因(yīn)1抗(kàng)體(tǐ)
別 名(míng)KAL; Adhesion molecule-like X-linked; ADMLX; Anosmin-1; HHA; KAL1; KALIG 1; KALIG1; Kallmann syndrome 1 sequence (anosmin 1); Kallmann syndrome interval gene 1; Kallmann syndrome protein; KALM; KALM_HUMAN; KMS.
詳(xiáng)細介紹：
規格:100ul
說(shuō) 明(míng) 書100ul
研(yán)究領域神(shén)經生物(wù)學 信號轉導(dǎo) 細(xì)胞骨(gǔ)架 細胞外(wài)基質(zhì)
抗(kàng)體來源(yuán)Rabbit
克隆(lóng)類型(xíng)Polyclonal
交叉反(fǎn)應 Human, Rat, Chicken, Dog, Pig, Horse, Sheep,
產品應(yīng)用ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量74kDa
細(xì)胞(bāo)定位(wèi)細胞(bāo)膜(mó)
性(xìng) 狀Lyophilized or Liquid
濃(nóng) 度1mg/ml
免 疫 原(yuán)KLH conjugated synthetic peptide derived from human AF-6/l Afadin
亞 型IgG
純化(huà)方法affinity purified by Protein A
儲 存(cún) 液(yè)0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存(cún)條(tiáo)件(jiàn)Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈(fèi). When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
相關(guān)資(zī)料(liào)：
產品(pǐn)介(jiè)紹background:
May be an adhesion-like molecule with anti-protease activity
Function:
Has a dual branch-promoting and guidance activity, which may play an important role in the patterning of mitral and tufted cell collaterals to the olfactory cortex (By similarity). Chemoattractant for fetal olfactory epithelial cells.
Subunit:
Interacts with FGFR1; this interaction does not interfere with FGF2-binding to FGFR1. Binds heparin. Heparin may promote or interfere with KAL1-FGFR1-FGF2 complex formation depending on the sequential order of its binding to the various constituents. For instance, heparin-KAL1 interaction favors subsequent binding to pre-existing binary FGFR1-FGF2 complex, while heparin-FGF2 complex does not interact with KAL1-FGFR1.
Subcellular Location:
Cell membrane; Peripheral membrane protein. Secreted. Note=Proteolytic cleavage may release it from the cell surface into the extracellular space.
Tissue Specificity:
Expressed in the cerebellum (at protein level).
Post-translational modifications:
N-glycosylated.
