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英文(wén)名(míng)稱Anti-AMIGO3/FITC
中文(wén)名(míng)稱:FITC標記的(dí)粘附(fù)分子(zǐ)IgG樣結(jié)構域(yù)蛋(dàn)白(bái)3抗體
別 名(míng)Adhesion molecule with Ig like domain 3; ALI3; Alivin 3; AMIGO 3; Amphoterin induced gene and ORF 3; Amphoterin induced protein 3 precursor.AMGO3_HUMAN
規格:100ul
說(shuō) 明(míng) 書100ul
研(yán)究(jiū)領域細胞(bāo)生物 免(miǎn)疫學(xué)
抗(kàng)體來(lái)源(yuán)Rabbit
克隆(lóng)類(lèi)型(xíng)Polyclonal
交叉(chā)反應 Human, Pig, Rabbit,
產(chǎn)品應用ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分(fēn) 子(zǐ) 量52kDa
細(xì)胞定(dìng)位細胞膜
性(xìng) 狀Lyophilized or Liquid
濃(nóng) 度1mg/ml
免 疫(yì) 原(yuán)KLH conjugated synthetic peptide derived from human AMIGO3
亞 型(xíng)IgG
純(chún)化(huà)方法(fǎ)affinity purified by Protein A
儲(chǔ) 存(cún) 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存(cún)條(tiáo)件(jiàn)Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品(pǐn)介(jiè)紹background:
The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO1, AMIGO2 and AMIGO3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain, and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. The AMIGO proteins can form complexes with each other, but can also bind itself. AMIGO1, also designated Alivin-2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO2 (Alivin-1) is crucial for depolarization-dependent survival. Similar to AMIGO1 and AMIGO2, AMIGO3 (Alivin-3) plays a role in homophilic and/or heterophilic cell-cell interaction and signal transduction.
Function:
AMIGO3 may mediate heterophilic cell-cell interaction and may also contribute to signal transduction through its intracellular domain.
Subunit:
Binds AMIGO1 or AMIGO2 (By similarity).
Subcellular Location:
Membrane; Single-pass type I membrane protein
Similarity:
Belongs to the immunoglobulin superfamily. AMIGO family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 6 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.
中文(wén)名(míng)稱:FITC標記的(dí)粘附(fù)分子(zǐ)IgG樣結(jié)構域(yù)蛋(dàn)白(bái)3抗體
別 名(míng)Adhesion molecule with Ig like domain 3; ALI3; Alivin 3; AMIGO 3; Amphoterin induced gene and ORF 3; Amphoterin induced protein 3 precursor.AMGO3_HUMAN
詳細介紹：
規格:100ul
說(shuō) 明(míng) 書100ul
研(yán)究(jiū)領域細胞(bāo)生物 免(miǎn)疫學(xué)
抗(kàng)體來(lái)源(yuán)Rabbit
克隆(lóng)類(lèi)型(xíng)Polyclonal
交叉(chā)反應 Human, Pig, Rabbit,
產(chǎn)品應用ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分(fēn) 子(zǐ) 量52kDa
細(xì)胞定(dìng)位細胞膜
性(xìng) 狀Lyophilized or Liquid
濃(nóng) 度1mg/ml
免 疫(yì) 原(yuán)KLH conjugated synthetic peptide derived from human AMIGO3
亞 型(xíng)IgG
純(chún)化(huà)方法(fǎ)affinity purified by Protein A
儲(chǔ) 存(cún) 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存(cún)條(tiáo)件(jiàn)Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相(xiāng)關資(zī)料：
產品(pǐn)介(jiè)紹background:
The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO1, AMIGO2 and AMIGO3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain, and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. The AMIGO proteins can form complexes with each other, but can also bind itself. AMIGO1, also designated Alivin-2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO2 (Alivin-1) is crucial for depolarization-dependent survival. Similar to AMIGO1 and AMIGO2, AMIGO3 (Alivin-3) plays a role in homophilic and/or heterophilic cell-cell interaction and signal transduction.
Function:
AMIGO3 may mediate heterophilic cell-cell interaction and may also contribute to signal transduction through its intracellular domain.
Subunit:
Binds AMIGO1 or AMIGO2 (By similarity).
Subcellular Location:
Membrane; Single-pass type I membrane protein
Similarity:
Belongs to the immunoglobulin superfamily. AMIGO family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 6 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.
