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FITC標(biāo)記的(dí)轉化生(shēng)長(cháng)因子β誘導(dǎo)蛋白3抗(kàng)體(半(bàn)胱(guāng)氨酸(suān)和絲氨酸(suān)富含(hán)核(hé)蛋(dàn)白(bái)1)

文字:[大(dà)][中(zhōng)][小] 2017-5-3    瀏(liú)覽(lǎn)次數:1318    

 FITC標記的(dí)轉化(huà)生長(cháng)因子(zǐ)β誘(yòu)導蛋白3抗體(半(bàn)胱氨酸(suān)和絲氨(ān)酸(suān)富含(hán)核蛋白1)                                                                                                                                                
英文(wén)名(míng)稱Anti-AXUD1/FITC
中文名稱:FITC標記(jì)的轉(zhuǎn)化生長(cháng)因子β誘導(dǎo)蛋白(bái)3抗體(tǐ)(半(bàn)胱(guāng)氨(ān)酸和絲氨酸富(fù)含核蛋白1)
別    名Axin 1 Up-regulated; Axin-1 up-regulated gene 1 protein; CSRN1_HUMAN; CSRNP-1; CSRNP1; Cysteine/serine-rich nuclear protein 1; DKFZp566F164; FAM130B; Protein URAX1; TAIP 3; TAIP-3; TGF beta induced apoptosis protein 3; TGF-beta-induced apoptosis protein 3; URAX1.  

詳細介(jiè)紹(shào):


規(guī)格(gé):100ul 
說(shuō) 明 書100ul  
研究(jiū)領(lǐng)域細胞生物  信號轉導  細胞周(zhōu)期(qī)蛋(dàn)白(bái)  轉(zhuǎn)錄調節因子  表(biǎo)觀遺傳學  
抗體來(lái)源Rabbit
克(kè)隆類型Polyclonal
交叉反應 Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep, 
產(chǎn)品(pǐn)應(yīng)用(yòng)IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分(fēn) 子 量64kDa
性    狀(zhuàng)Lyophilized or Liquid
濃    度(dù)1mg/ml
免 疫 原(yuán)KLH conjugated synthetic peptide derived from human AXUD1
亞(yà)    型(xíng)IgG
純化(huà)方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保(bǎo)存條(tiáo)件(jiàn)Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

相(xiāng)關(guān)資(zī)料:


產(chǎn)品介(jiè)紹(shào)background:
This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function. [provided by RefSeq, Jul 2008].

Function:
Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity. May have a tumor-suppressor function. May play a role in apoptosis. 

Subcellular Location:
Nucleus

Tissue Specificity:
Ubiquitous. Most abundantly expressed in lung, placenta, skeletal muscle, pancreas and leukocyte. Frequently down-regulated in lung, kidney, liver and colon cancers compared with their corresponding normal tissues.

Similarity:
Belongs to the AXUD1 family.

Database links:
UniProtKB/Swiss-Prot: Q96S65.2

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