產品(pǐn)中心
標(biāo)記(jì)一抗
FITC標記的(dí)整合(hé)素樣金屬(shǔ)蛋白酶(méi)與凝血(xiě)酶(méi)8型抗體
英(yīng)文名稱Anti-ADAMTS8/FITC
中(zhōng)文名稱(chēng):FITC標(biāo)記的整合(hé)素(sù)樣(yàng)金(jīn)屬(shǔ)蛋(dàn)白(bái)酶與凝血(xiě)酶8型抗體
別 名A disintegrin and metalloproteinase with thrombospondin motifs 8; ADAMTS 8; METH 2; METH 8; METH8; A disintegrin like and metalloprotease reprolysin type with thrombospondin type 1 motif 8; A disintegrin like and metalloprotease with thrombospondin type 1 motif 8; ADAM metallopeptidase with thrombospondin type 1 motif 8; ADAM TS 8; ADAM TS8; METH2; ATS8_HUMAN.
規格:100ul
說(shuō) 明 書100ul
研(yán)究(jiū)領(lǐng)域腫瘤 細胞生物 免疫學(xué) 信(xìn)號(hào)轉導 細(xì)胞粘附分(fēn)子
抗(kàng)體來(lái)源(yuán)Rabbit
克隆(lóng)類型Polyclonal
交叉(chā)反(fǎn)應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Horse,
產品應用(yòng)IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量(liáng)74kDa
性 狀Lyophilized or Liquid
濃 度(dù)1mg/ml
免 疫(yì) 原KLH conjugated synthetic peptide derived from human ADAMTS8
亞(yà) 型(xíng)IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保(bǎo)存(cún)條(tiáo)件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品(pǐn)介紹(shào)background:
ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, versican and brevican. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. A member of the metalloproteinase family containing disintegrin like domains (ADAMs), the function of ADAMTS8 is still poorly understood. ADAMTS8 contains the canonical HExxHxxxxxH zinc metalloproteinase motif, and has been shown to be proteolytically active on a range of substrates. ADAMTS8 is inhibited by the endogenous MMP inhibitors, TIMP1, 2, 3 and 4, but most efficiently by TIMP3. In addition to the metalloprotease domain, ADAMTS8 has a propeptide domain, a Prohormone Convertase (PC, furin) cleavage site, a cysteine rich domain and thrombospondin 1 like domains.
中(zhōng)文名稱(chēng):FITC標(biāo)記的整合(hé)素(sù)樣(yàng)金(jīn)屬(shǔ)蛋(dàn)白(bái)酶與凝血(xiě)酶8型抗體
別 名A disintegrin and metalloproteinase with thrombospondin motifs 8; ADAMTS 8; METH 2; METH 8; METH8; A disintegrin like and metalloprotease reprolysin type with thrombospondin type 1 motif 8; A disintegrin like and metalloprotease with thrombospondin type 1 motif 8; ADAM metallopeptidase with thrombospondin type 1 motif 8; ADAM TS 8; ADAM TS8; METH2; ATS8_HUMAN.
詳細介紹：
規格:100ul
說(shuō) 明 書100ul
研(yán)究(jiū)領(lǐng)域腫瘤 細胞生物 免疫學(xué) 信(xìn)號(hào)轉導 細(xì)胞粘附分(fēn)子
抗(kàng)體來(lái)源(yuán)Rabbit
克隆(lóng)類型Polyclonal
交叉(chā)反(fǎn)應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Horse,
產品應用(yòng)IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量(liáng)74kDa
性 狀Lyophilized or Liquid
濃 度(dù)1mg/ml
免 疫(yì) 原KLH conjugated synthetic peptide derived from human ADAMTS8
亞(yà) 型(xíng)IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保(bǎo)存(cún)條(tiáo)件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相(xiāng)關(guān)資料：
產品(pǐn)介紹(shào)background:
ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, versican and brevican. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. A member of the metalloproteinase family containing disintegrin like domains (ADAMs), the function of ADAMTS8 is still poorly understood. ADAMTS8 contains the canonical HExxHxxxxxH zinc metalloproteinase motif, and has been shown to be proteolytically active on a range of substrates. ADAMTS8 is inhibited by the endogenous MMP inhibitors, TIMP1, 2, 3 and 4, but most efficiently by TIMP3. In addition to the metalloprotease domain, ADAMTS8 has a propeptide domain, a Prohormone Convertase (PC, furin) cleavage site, a cysteine rich domain and thrombospondin 1 like domains.
