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英(yīng)文(wén)名稱(chēng) Anti-ADH5
中文(wén)名(míng)稱 乙醇脫(tuō)氫酶5抗體
別(bié) 名 ADH 3; ADH5; ADHX; ADHX_HUMAN; Alcohol dehydrogenase (class III) chi polypeptide; alcohol dehydrogenase 5 (class III) chi polypeptide; Alcohol dehydrogenase 5; Alcohol dehydrogenase class 3; Alcohol dehydrogenase class chi chain; Alcohol dehydrogenase class III; Alcohol dehydrogenase class-3; Alcohol dehydrogenase class-III; class III alcohol dehydrogenase 5 chi subunit; FALDH; FDH; formaldehyde dehydrogenase; Glutathione dependent formaldehyde dehydrogenase; Glutathione-dependent formaldehyde dehydrogenase; GSH-FDH; hydroxymethyllutathione dehydrogenase; S-(hydroxymethyl)glutathione dehydrogenase.
濃 度(dù) 1mg/1ml
規 格(gé) 0.2ml/200μg
抗體來(lái)源 Rabbit
克隆類型 polyclonal
交(jiāo)叉反(fǎn)應 Human, Mouse, Rat
產品(pǐn)類(lèi)型 一抗
研(yán)究領域 腫瘤(liú) 細胞(bāo)生物 信號(hào)轉(zhuǎn)導 新陳代謝
蛋白分子量(liáng) predicted molecular weight: 40kDa
性 狀 Lyophilized or Liquid
免 疫(yì) 原 KLH conjugated synthetic peptide derived from human ADH5
亞(yà) 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應用(yòng) WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蠟切片(piàn)需做(zuò)抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條(tiáo)件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品(pǐn)介(jiè)紹 The alcohol dehydrogenase family of proteins metabolize a wide variety of substrates, including retinol, hydroxysteroids, ethanol, aliphatic alcohols and lipid peroxidation products. ADH5 (alcohol dehydrogenase 5 (class III)), also known as FDH (formaldehyde dehydrogenase), ADHX, ADH-3 or GSNOR, is a 374 amino acid cytoplasmic protein that belongs to the class III subfamily of alcohol dehydrogenases. Expressed ubiquitously, ADH5 uses iron as a cofactor to catalytically oxidize both long-chain primary alcohols and S-hydroxymethyl-glutathione, a product formed spontaneously between formaldehyde and glutathione. ADH5 exists as a homodimer and, via its ability to oxidize S-hydroxymethyl-glutathione and, thus, eliminate formaldehyde, functions as an important component of cellular metabolism. Genetic variations in the gene encoding ADH5 may affect drug and alcohol dependence in humans.
Function : Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione.
Subunit : Homodimer.
Subcellular Location : Cytoplasm.
Similarity : Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
Database links : UniProtKB/Swiss-Prot: P11766.4
中文(wén)名(míng)稱 乙醇脫(tuō)氫酶5抗體
別(bié) 名 ADH 3; ADH5; ADHX; ADHX_HUMAN; Alcohol dehydrogenase (class III) chi polypeptide; alcohol dehydrogenase 5 (class III) chi polypeptide; Alcohol dehydrogenase 5; Alcohol dehydrogenase class 3; Alcohol dehydrogenase class chi chain; Alcohol dehydrogenase class III; Alcohol dehydrogenase class-3; Alcohol dehydrogenase class-III; class III alcohol dehydrogenase 5 chi subunit; FALDH; FDH; formaldehyde dehydrogenase; Glutathione dependent formaldehyde dehydrogenase; Glutathione-dependent formaldehyde dehydrogenase; GSH-FDH; hydroxymethyllutathione dehydrogenase; S-(hydroxymethyl)glutathione dehydrogenase.
詳(xiáng)細介紹(shào)：
濃 度(dù) 1mg/1ml
規 格(gé) 0.2ml/200μg
抗體來(lái)源 Rabbit
克隆類型 polyclonal
交(jiāo)叉反(fǎn)應 Human, Mouse, Rat
產品(pǐn)類(lèi)型 一抗
研(yán)究領域 腫瘤(liú) 細胞(bāo)生物 信號(hào)轉(zhuǎn)導 新陳代謝
蛋白分子量(liáng) predicted molecular weight: 40kDa
性 狀 Lyophilized or Liquid
免 疫(yì) 原 KLH conjugated synthetic peptide derived from human ADH5
亞(yà) 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應用(yòng) WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蠟切片(piàn)需做(zuò)抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條(tiáo)件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
相關資(zī)料(liào)：
產(chǎn)品(pǐn)介(jiè)紹 The alcohol dehydrogenase family of proteins metabolize a wide variety of substrates, including retinol, hydroxysteroids, ethanol, aliphatic alcohols and lipid peroxidation products. ADH5 (alcohol dehydrogenase 5 (class III)), also known as FDH (formaldehyde dehydrogenase), ADHX, ADH-3 or GSNOR, is a 374 amino acid cytoplasmic protein that belongs to the class III subfamily of alcohol dehydrogenases. Expressed ubiquitously, ADH5 uses iron as a cofactor to catalytically oxidize both long-chain primary alcohols and S-hydroxymethyl-glutathione, a product formed spontaneously between formaldehyde and glutathione. ADH5 exists as a homodimer and, via its ability to oxidize S-hydroxymethyl-glutathione and, thus, eliminate formaldehyde, functions as an important component of cellular metabolism. Genetic variations in the gene encoding ADH5 may affect drug and alcohol dependence in humans.
Function : Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione.
Subunit : Homodimer.
Subcellular Location : Cytoplasm.
Similarity : Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
Database links : UniProtKB/Swiss-Prot: P11766.4
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